apalutamide will lower the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with drugs which are CYP3A4 substrates may lead to decreased publicity to these remedies.Utilizing this medicine with any of the following medic

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